TDRD3

Across TCGA patient cohorts, TDRD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,080 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TDRD3-associated proteins across cancer lineages are ESD, TOP3B, and ARHGEF7. Each is linked with TDRD3 in more than 5 cancer types. Because this analysis shows association rather than direction, both TDRD3-to-partner and partner-to-TDRD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TDRD3 versus ESD in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD3→partner) and Y-score (partner→TDRD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ESD →	+0.361	+0.371	<.001	<.001	3	6
OV	TOP3B →	+0.292	+0.485	<.001	.001	3	6
GBM	ARHGEF7 →	+0.255	+0.390	<.001	<.001	3	6
BRCA	VEZF1 →	+0.468	+0.338	<.001	.006	3	6
BRCA	GPALPP1 →	+0.390	+0.566	<.001	<.001	3	6
GBM	RPL7 →	-0.335	-0.378	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,080 associations by consensus.

TDRD3 vs ESD — BRCA

Explore this scatter interactively →