TDRD3

Across TCGA cell cohorts, TDRD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,051 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TDRD3-associated GO terms across cancer lineages are Ribosomal protein import into nucleus, Copper ion export, and Negative regulation of hematopoietic stem cell differentiation. Each is linked with TDRD3 in more than 10 cancer types. Because this analysis shows association rather than direction, both TDRD3-to-partner and partner-to-TDRD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal protein import into nucleus grouped by TDRD3-low versus TDRD3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD3→partner) and Y-score (partner→TDRD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Ribosomal protein import into nucleus →	+0.090	+0.770	<.001	<.001	3	11
OVARY	Copper ion export →	-0.193	-0.943	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of hematopoietic stem cell differentiation →	+0.162	+0.807	<.001	<.001	3	10
BONE	Hemostasis →	-0.121	-0.995	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Nucleotide-excision repair, DNA gap filling →	+0.113	+0.880	<.001	<.001	3	10
BONE	Blood coagulation →	-0.144	-1.143	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,051 associations by consensus.

Ribosomal protein import into nucleus by TDRD3 expression — LARGE_INTESTINE

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