Across TCGA cell cohorts, TDRD15 mutation is significantly associated with the mutation status of many other genes, with 3,309 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TDRD15-associated genes across cancer lineages are SPTBN4, FAT4, and NCOR1. Each is linked with TDRD15 in more than 4 cancer types. Because this analysis shows association rather than direction, both TDRD15-to-partner and partner-to-TDRD15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD15→partner) and Y-score (partner→TDRD15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SPTBN4 →	+2.823	+3.665	.008	.008	1	5
LARGE_INTESTINE	FAT4 →	+1.182	+2.700	.004	.004	1	5
STOMACH	NCOR1 →	+3.584	+3.584	.006	.006	1	5
BLOOD_Leukemia	SETD1B →	+2.653	+4.452	.001	.001	1	5
BLOOD_Leukemia	CACNA1B →	+3.338	+4.083	.003	.003	1	5
CNS	HELZ →	+3.055	+3.786	.006	.006	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,309 associations by consensus.

Exploration

TDRD15 survival (RNA) · tumor vs normal (RNA) · all TDRD15 data types