TDRD12

Across TCGA patient cohorts, TDRD12 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,928 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TDRD12-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, Microtubule polymerization, and Regulation of chromosome organization. Each is linked with TDRD12 in more than 20 cancer types. Because this analysis shows association rather than direction, both TDRD12-to-partner and partner-to-TDRD12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process grouped by TDRD12-low versus TDRD12-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD12→partner) and Y-score (partner→TDRD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Nuclear-transcribed mRNA catabolic process →	+0.107	+0.548	<.001	<.001	3	21
STAD	Microtubule polymerization →	+0.071	+0.423	<.001	<.001	3	20
ESCA	Regulation of chromosome organization →	+0.103	+0.647	<.001	<.001	2	21
STAD	mRNA 3'-end processing →	+0.077	+0.428	<.001	<.001	3	19
ESCA	Regulation of DNA-templated transcription initiation →	+0.089	+0.272	<.001	<.001	3	19
ESCA	Positive regulation of chromosome organization →	+0.106	+0.531	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,928 associations by consensus.

Nuclear-transcribed mRNA catabolic process by TDRD12 expression — ESCA

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