TDRD12

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TDRD12 protein abundance is significantly associated with the RNA expression of many other genes, with 201 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TDRD12-associated genes across cancer lineages are EIF4A1P1, OR9L1P, and OR1P1. Each is linked with TDRD12 in more than 1 cancer types. Because this analysis shows association rather than direction, both TDRD12-to-partner and partner-to-TDRD12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TDRD12 versus EIF4A1P1 in GBM, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD12→partner) and Y-score (partner→TDRD12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMEIF4A1P1 →+0.296+1.885.005.00931
GBMOR9L1P →+0.156+1.885.008.00931
GBMOR1P1 →+0.146+1.885.005.00931
GBMMIR548AR →+1.503+1.885.001.00931
GBMMIR8053 →+1.460+1.885<.001.00931
UCECRAPGEFL1 →+1.367+1.753<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 201 associations by consensus.

TDRD12 vs EIF4A1P1 — GBM

Per-sample scatter of TDRD12 vs EIF4A1P1 in GBM (Pearson r = 0.80).

Explore this scatter interactively →

Exploration