TDRD1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TDRD1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,890 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TDRD1-associated genes across cancer lineages are APOL1, GDA, and ANXA11. Each is linked with TDRD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TDRD1-to-partner and partner-to-TDRD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TDRD1 versus APOL1 in UCEC, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD1→partner) and Y-score (partner→TDRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAPOL1 →+1.284+1.800.002<.00131
UCECGDA →+3.004+1.800.001<.00131
UCECANXA11 →+0.846+2.280.001.00431
UCECACO1 →+1.117+2.032.004.00331
UCECFAM124B →-1.900-2.262.002<.00131
UCECEML2 →+0.615+1.800.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,890 associations by consensus.

TDRD1 vs APOL1 — UCEC

Per-sample scatter of TDRD1 vs APOL1 in UCEC (Pearson r = 0.84).

Explore this scatter interactively →

Exploration