TDRD1

Across TCGA patient cohorts, TDRD1 mutation is significantly associated with the RNA expression of many other genes, with 3,535 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TDRD1-associated genes across cancer lineages are MIR629, TAAR7P, and LIG1. Each is linked with TDRD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TDRD1-to-partner and partner-to-TDRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR629 grouped by TDRD1-low versus TDRD1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD1→partner) and Y-score (partner→TDRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MIR629 →	+0.247	+4.354	<.001	.006	3	3
HNSC	TAAR7P →	+0.056	+4.187	<.001	.006	3	3
UCEC	LIG1 →	+0.358	+1.981	.001	<.001	3	3
UCEC	ANAPC15 →	+0.315	+1.616	.001	.002	3	3
UCEC	IGHMBP2 →	+0.241	+2.178	<.001	<.001	3	3
UCEC	RSAD1 →	+0.331	+1.469	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,535 associations by consensus.

MIR629 by TDRD1 expression — LIHC

Explore this box plot interactively →