TDRD1

Across TCGA cell cohorts, TDRD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 792 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TDRD1-associated GO terms across cancer lineages are Spindle midzone assembly, Protein K48-linked deubiquitination, and Regulation of tolerance induction. Each is linked with TDRD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TDRD1-to-partner and partner-to-TDRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle midzone assembly grouped by TDRD1-low versus TDRD1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD1→partner) and Y-score (partner→TDRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Spindle midzone assembly →	+0.128	+0.251	.005	.008	3	3
SOFT_TISSUE	Protein K48-linked deubiquitination →	+0.050	+0.180	<.001	.007	3	3
SOFT_TISSUE	Regulation of tolerance induction →	-0.215	-0.187	<.001	.005	3	2
LUNG_NSCLC_LUAD	Protein import into peroxisome matrix, substrate release →	-0.063	-0.784	.002	.009	3	2
BREAST	Regulation of extracellular matrix disassembly →	-0.144	-1.567	<.001	<.001	3	2
BREAST	Morula formation →	+0.565	+1.637	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 792 associations by consensus.

Spindle midzone assembly by TDRD1 expression — SOFT_TISSUE

Explore this box plot interactively →