TDGP1

Across TCGA patient cohorts, TDGP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,538 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TDGP1-associated GO terms across cancer lineages are RNA localization, Mitotic sister chromatid cohesion, and Establishment of RNA localization. Each is linked with TDGP1 in more than 26 cancer types. Because this analysis shows association rather than direction, both TDGP1-to-partner and partner-to-TDGP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA localization grouped by TDGP1-low versus TDGP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TDGP1→partner) and Y-score (partner→TDGP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	RNA localization →	+0.051	+0.170	<.001	<.001	3	27
ESCA	Mitotic sister chromatid cohesion →	+0.099	+0.284	<.001	<.001	3	26
ESCA	Establishment of RNA localization →	+0.054	+0.171	<.001	<.001	3	25
DLBC	Maintenance of cell number →	+0.043	+0.086	.001	<.001	2	26
DLBC	Interstrand cross-link repair →	+0.056	+0.081	<.001	.001	3	24
STAD	Positive regulation of mRNA processing →	+0.078	+0.178	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,538 associations by consensus.

RNA localization by TDGP1 expression — ESCA

Explore this box plot interactively →