Across TCGA pan-cancer cohorts, TDGF1P2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TDGF1P2’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where TDGF1P2 RNA is repressed in tumor relative to normal tissue. In most cancer types TDGF1P2 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.
KICH, THCA, and STAD are the cancer types where TDGF1P2 tumor–normal differential expression is most reproducible.