TCTN3

Across TCGA patient cohorts, TCTN3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,103 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TCTN3-associated genes across cancer lineages are GZMH, ELMOD1, and MRPL15. Each is linked with TCTN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCTN3-to-partner and partner-to-TCTN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TCTN3 versus GZMH in OV, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCTN3→partner) and Y-score (partner→TCTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GZMH →	-1.244	-0.646	.003	.002	3	2
PDAC	ELMOD1 →	+0.245	+0.463	<.001	<.001	3	2
UCEC	MRPL15 →	-0.726	-0.456	<.001	<.001	3	2
OV	CASP1 →	-0.834	-0.602	.004	.004	3	2
OV	LACTB2 →	-0.789	-0.534	<.001	.001	3	2
LUAD	MAL2 →	-1.199	-0.251	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,103 associations by consensus.

TCTN3 vs GZMH — OV

Explore this scatter interactively →