TCTN3

Across TCGA patient cohorts, TCTN3 mutation is significantly associated with the RNA expression of many other genes, with 254 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCTN3-associated genes across cancer lineages are ZNF734P, RNA5SP387, and LINC02854. Each is linked with TCTN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCTN3-to-partner and partner-to-TCTN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF734P grouped by TCTN3-low versus TCTN3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCTN3→partner) and Y-score (partner→TCTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF734P →	+0.090	+5.646	.001	.004	3	2
BRCA	RNA5SP387 →	+1.626	+5.288	<.001	.006	3	2
SKCM	LINC02854 →	+0.037	+5.488	<.001	.001	3	2
SKCM	PRELID3BP2 →	+0.102	+5.488	<.001	.001	3	2
COAD	OR9Q2 →	+0.047	+4.721	<.001	.004	3	2
COAD	MTCO1P56 →	+0.275	+4.917	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 254 associations by consensus.

ZNF734P by TCTN3 expression — BRCA

Explore this box plot interactively →