TCTN3

Across TCGA cell cohorts, TCTN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,733 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TCTN3-associated GO terms across cancer lineages are Ornithine metabolic process, Regulation of smoothened signaling pathway, and Ceramide metabolic process. Each is linked with TCTN3 in more than 14 cancer types. Because this analysis shows association rather than direction, both TCTN3-to-partner and partner-to-TCTN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ornithine metabolic process grouped by TCTN3-low versus TCTN3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCTN3→partner) and Y-score (partner→TCTN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Ornithine metabolic process →	+0.139	+0.936	.001	<.001	3	15
OVARY	Regulation of smoothened signaling pathway →	+0.051	+0.706	.001	.001	3	11
OESOPHAGUS	Ceramide metabolic process →	+0.095	+1.012	<.001	.007	3	10
URINARY_TRACT	Melanosome assembly →	+0.088	+0.643	<.001	<.001	3	10
BONE	Lipid modification →	+0.046	+0.587	.003	<.001	3	9
PANCREAS	Melanosome organization →	+0.079	+0.739	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,733 associations by consensus.

Ornithine metabolic process by TCTN3 expression — LUNG_SCLC

Explore this box plot interactively →