Across TCGA patient cohorts, TCTN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,298 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TCTN1-associated proteins across cancer lineages are LZTFL1, IFT122, and IFT74. Each is linked with TCTN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TCTN1-to-partner and partner-to-TCTN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TCTN1→partner) and Y-score (partner→TCTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LZTFL1 →	+0.657	+1.014	<.001	<.001	3	7
BRCA	IFT122 →	+0.384	+1.010	<.001	<.001	3	6
BRCA	IFT74 →	+0.477	+1.033	<.001	<.001	3	6
UCEC	CETN2 →	+0.346	+0.528	<.001	<.001	3	6
BRCA	IFT140 →	+0.541	+1.057	<.001	<.001	3	6
BRCA	WDR54 →	+0.490	+0.649	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,298 associations by consensus.

Exploration

TCTN1 survival (RNA) · tumor vs normal (RNA) · all TCTN1 data types