Across TCGA cell cohorts, TCTEX1D4 mutation is significantly associated with the drug of many other genes, with 19 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TCTEX1D4-associated genes across cancer lineages are AZD5153, JAK1_8709, and Pelitinib. Each is linked with TCTEX1D4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCTEX1D4-to-partner and partner-to-TCTEX1D4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCTEX1D4→partner) and Y-score (partner→TCTEX1D4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AZD5153 →	+0.639	+2.871	.006	.021	3	1
LARGE_INTESTINE	JAK1_8709 →	+0.427	+2.871	.022	.021	3	1
LARGE_INTESTINE	Pelitinib →	+0.685	+3.008	.025	.016	3	1
LARGE_INTESTINE	TPCA-1 →	+0.552	+3.008	.013	.016	3	1
LARGE_INTESTINE	SNX-2112 →	+0.690	+2.874	.039	.021	3	1
LARGE_INTESTINE	ARRY-520 →	+0.725	+2.807	.041	.044	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

TCTEX1D4 survival (RNA) · tumor vs normal (RNA) · all TCTEX1D4 data types