Across TCGA pan-cancer cohorts, TCTEX1D2 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TCTEX1D2 data layer compared with 25 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher TCTEX1D2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TCTEX1D2 expression acts as an unfavorable survival marker.

SKCM, ESCA, and COAD are the cancer types where TCTEX1D2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	III,IV	0.111	0.814	<.001	24	view →
ESCA	DFS	Median	All	0.045	0.533	<.001	12	view →
COAD	OS	Median	All	0.556	0.870	.024	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: TCTEX1D2 tumor-vs-normal RNA expression · all TCTEX1D2 data types