Across TCGA patient cohorts, TCTE3 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCTE3-associated genes across cancer lineages are ERK2, JNK_pT183_Y185, and MEK1. Each is linked with TCTE3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCTE3-to-partner and partner-to-TCTE3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCTE3→partner) and Y-score (partner→TCTE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.298	+3.321	.003	.010	3	1
UCEC	JNK_pT183_Y185 →	-0.222	-2.999	.011	.035	3	1
UCEC	MEK1 →	+0.444	+3.000	.020	.036	3	1
UCEC	mTOR →	-0.228	-2.999	.007	.035	3	1
UCEC	PEA-15_pS116 →	+0.655	+3.321	<.001	.010	3	1
UCEC	XBP1 →	-0.237	-2.986	.001	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

TCTE3 survival (RNA) · tumor vs normal (RNA) · all TCTE3 data types