TCTE1

Across TCGA patient cohorts, TCTE1 mutation is significantly associated with the RNA expression of many other genes, with 4,434 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCTE1-associated genes across cancer lineages are EIF4EBP2P3, DCP1A, and PCCA-DT. Each is linked with TCTE1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TCTE1-to-partner and partner-to-TCTE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF4EBP2P3 grouped by TCTE1-low versus TCTE1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCTE1→partner) and Y-score (partner→TCTE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EIF4EBP2P3 →	+0.149	+5.303	<.001	.006	3	3
UCEC	DCP1A →	+0.452	+2.850	.001	.001	3	2
UCEC	PCCA-DT →	+0.491	+1.906	<.001	.001	3	2
UCEC	TUBGCP5 →	+0.388	+1.855	<.001	.002	3	2
UCEC	UHRF1 →	+1.006	+2.546	<.001	<.001	3	2
UCEC	PIGW →	+0.592	+2.736	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,434 associations by consensus.

EIF4EBP2P3 by TCTE1 expression — HNSC

Explore this box plot interactively →