TCTE1

Across TCGA cell cohorts, TCTE1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TCTE1-associated genes across cancer lineages are SIGLEC6, TPD52L3, and LIPN. Each is linked with TCTE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCTE1-to-partner and partner-to-TCTE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIGLEC6 grouped by TCTE1-low versus TCTE1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCTE1→partner) and Y-score (partner→TCTE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SIGLEC6 →	+0.126	+3.544	.001	.007	3	1
SKIN	TPD52L3 →	+0.002	+3.700	<.001	.009	3	1
SKIN	LIPN →	+0.012	+3.562	<.001	.002	3	1
SKIN	CARD18 →	+0.081	+3.669	.002	<.001	3	1
LARGE_INTESTINE	C1QTNF7 →	+0.125	+5.108	<.001	<.001	3	1
LARGE_INTESTINE	PPDPFL →	+0.034	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

SIGLEC6 by TCTE1 expression — SKIN

Explore this box plot interactively →