TCP11X1

Across TCGA patient cohorts, TCP11X1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCP11X1-associated genes across cancer lineages are RNU6-161P, TSPY25P, and MIR4752. Each is linked with TCP11X1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCP11X1-to-partner and partner-to-TCP11X1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-161P grouped by TCP11X1-low versus TCP11X1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCP11X1→partner) and Y-score (partner→TCP11X1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-161P →	+0.271	+8.066	<.001	.007	3	1
UCEC	TSPY25P →	+0.044	+8.066	<.001	.007	3	1
UCEC	MIR4752 →	+0.618	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

RNU6-161P by TCP11X1 expression — UCEC

Explore this box plot interactively →