TCP11L1

Across TCGA cell cohorts, TCP11L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,155 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TCP11L1-associated GO terms across cancer lineages are Retrograde transport, endosome to Golgi, Phosphatidylinositol biosynthetic process, and Macroautophagy. Each is linked with TCP11L1 in more than 15 cancer types. Because this analysis shows association rather than direction, both TCP11L1-to-partner and partner-to-TCP11L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde transport, endosome to Golgi grouped by TCP11L1-low versus TCP11L1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCP11L1→partner) and Y-score (partner→TCP11L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Retrograde transport, endosome to Golgi →	+0.087	+1.172	<.001	.001	3	16
BONE	Phosphatidylinositol biosynthetic process →	+0.066	+1.269	<.001	<.001	3	14
BLOOD_Myeloma	Macroautophagy →	+0.071	+0.888	<.001	<.001	3	14
BONE	Regulation of hippo signaling →	+0.118	+1.422	<.001	<.001	3	13
OESOPHAGUS	Phosphatidylinositol metabolic process →	+0.053	+1.327	.003	.007	2	14
BONE	Regulation of protein K48-linked ubiquitination →	+0.179	+1.462	<.001	<.001	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,155 associations by consensus.

Retrograde transport, endosome to Golgi by TCP11L1 expression — KIDNEY

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