Across TCGA pan-cancer cohorts, TCP10L3 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TCP10L3 data layer compared with 13 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TCP10L3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TCP10L3 expression acts as an unfavorable survival marker.

COAD and SARC are the cancer types where TCP10L3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.001	0.871	<.001	12	view →
SARC	DFS	Median	All	0.098	0.591	.010	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TCP10L3 tumor-vs-normal RNA expression · all TCP10L3 data types