Across TCGA patient cohorts, TCN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,417 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TCN2-associated proteins across cancer lineages are RENBP, MYO1F, and NCKAP1L. Each is linked with TCN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both TCN2-to-partner and partner-to-TCN2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TCN2→partner) and Y-score (partner→TCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RENBP →	+0.438	+0.372	<.001	.001	3	8
GBM	MYO1F →	+0.533	+0.461	<.001	<.001	3	7
OV	NCKAP1L →	+0.532	+0.844	.002	.009	3	7
BRCA	CYBB →	+0.594	+0.540	<.001	<.001	3	7
OV	FMNL1 →	+0.535	+1.185	<.001	<.001	3	7
HNSC	LCP2 →	+0.439	+0.796	<.001	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,417 associations by consensus.

Exploration

TCN2 survival (RNA) · tumor vs normal (RNA) · all TCN2 data types