Across TCGA patient cohorts, TCN2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,333 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TCN2-associated genes across cancer lineages are LILRB3, DOK2, and CTSZ. Each is linked with TCN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TCN2-to-partner and partner-to-TCN2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCN2→partner) and Y-score (partner→TCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LILRB3 →	+1.150	+0.539	<.001	.002	3	4
BRCA	DOK2 →	+1.544	+0.629	<.001	.004	3	3
CCRCC	CTSZ →	+0.824	+0.382	<.001	.002	3	3
GBM	PRR16 →	+0.619	+0.420	.004	.001	3	3
HNSC	GIMAP1 →	+0.632	+0.382	.001	.003	3	3
HNSC	CTSS →	+1.370	+0.425	.008	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,333 associations by consensus.

Exploration

TCN2 survival (RNA) · tumor vs normal (RNA) · all TCN2 data types