Across TCGA cell cohorts, TCN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,942 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TCN2-associated GO terms across cancer lineages are Regulation of proteolysis, Intrinsic apoptotic signaling pathway, and Barbed-end actin filament capping. Each is linked with TCN2 in more than 11 cancer types. Because this analysis shows association rather than direction, both TCN2-to-partner and partner-to-TCN2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCN2→partner) and Y-score (partner→TCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of proteolysis →	+0.111	+1.622	.001	<.001	3	12
BLOOD_Lymphoma	Intrinsic apoptotic signaling pathway →	+0.052	+1.515	<.001	<.001	3	12
BREAST	Barbed-end actin filament capping →	+0.181	+1.869	<.001	<.001	3	11
BREAST	Actin filament capping →	+0.154	+1.218	<.001	<.001	3	11
BREAST	Viral process →	+0.083	+1.309	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Apoptotic signaling pathway →	+0.048	+1.413	.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,942 associations by consensus.

Exploration

TCN2 survival (RNA) · tumor vs normal (RNA) · all TCN2 data types