Across TCGA cell cohorts, TCN2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TCN2-associated genes across cancer lineages are OR2T2, CCDC172, and LCE2A. Each is linked with TCN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCN2-to-partner and partner-to-TCN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCN2→partner) and Y-score (partner→TCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	OR2T2 →	+0.036	+5.169	<.001	.004	3	1
BLOOD_Leukemia	CCDC172 →	+0.046	+5.201	.005	.006	3	1
BLOOD_Leukemia	LCE2A →	+0.071	+5.969	<.001	.001	3	1
BLOOD_Leukemia	IFNA4 →	+0.058	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

TCN2 survival (RNA) · tumor vs normal (RNA) · all TCN2 data types