TCN1

Across TCGA pan-cancer cohorts, TCN1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TCN1 data layer compared with 27 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TCN1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TCN1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, UCEC, and PDAC are the cancer types where TCN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.209	0.740	<.001	43	view →
UCEC	DFS	Quartile	All	0.966	0.689	.007	8	view →
PDAC	OS	Median	III,IV	0.594	0.912	.014	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TCN1–LUAD (OS)

Open the LUAD breakdown →