TCN1

Across TCGA patient cohorts, TCN1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,603 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TCN1-associated genes across cancer lineages are SLPI, TREM1, and SAA2. Each is linked with TCN1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TCN1-to-partner and partner-to-TCN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TCN1 versus SLPI in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCN1→partner) and Y-score (partner→TCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLPI →	+2.570	+1.044	<.001	<.001	3	6
COAD	TREM1 →	+1.809	+1.058	.001	<.001	3	6
GBM	SAA2 →	+1.794	+0.961	<.001	<.001	3	6
COAD	HCAR2 →	+4.132	+1.432	<.001	.002	3	6
COAD	CXCL8 →	+3.194	+0.940	.002	.005	3	6
LSCC	CXCR2 →	+1.094	+1.112	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,603 associations by consensus.

TCN1 vs SLPI — BRCA

Explore this scatter interactively →