Across TCGA patient cohorts, TCL6 mutation is significantly associated with the RNA expression of many other genes, with 3,618 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCL6-associated genes across cancer lineages are RAD23B, GPATCH11, and RNU6-929P. Each is linked with TCL6 in more than 2 cancer types. Because this analysis shows association rather than direction, both TCL6-to-partner and partner-to-TCL6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCL6→partner) and Y-score (partner→TCL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAD23B →	+0.517	+3.470	.001	.002	3	3
UCEC	GPATCH11 →	+0.542	+3.032	<.001	<.001	3	3
LUAD	RNU6-929P →	+0.158	+4.754	<.001	.002	3	3
LUAD	RNA5SP468 →	+0.213	+2.811	.008	.003	3	3
UCEC	ZNF367 →	+0.830	+2.662	<.001	<.001	3	3
SKCM	CDK1 →	+0.627	+2.540	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,618 associations by consensus.

Exploration

TCL6 survival (RNA) · tumor vs normal (RNA) · all TCL6 data types