TCIRG1

Across TCGA pan-cancer cohorts, TCIRG1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TCIRG1 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TCIRG1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TCIRG1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

COAD, PDAC, and LUAD are the cancer types where TCIRG1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.882	1.000	.015	84	view →
PDAC	DFS	Median	All	0.311	0.507	<.001	49	view →
LUAD	DFS	Quartile	All	0.793	0.983	.001	34	view →
CCRCC	OS	Median	All	0.748	0.922	.004	19	view →
LSCC	DFS	Median	III,IV	1.000	0.867	.045	2	view →
HNSC	DFS	Median	III,IV	0.939	1.000	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TCIRG1–COAD (DFS)

Open the COAD breakdown →