TCIM

Across TCGA pan-cancer cohorts, TCIM RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated TCIM data layer compared with 2 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher TCIM RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TCIM expression acts as an unfavorable survival marker, although some lineages such as THCA and KICH show a favorable association.

STAD, KIRP, and THCA are the cancer types where TCIM RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Median	All	0.476	0.624	<.001	124	view →
KIRP	DFS	Tertile	II,III,IV	0.489	0.872	<.001	96	view →
THCA	DFS	Quartile	All	0.949	0.855	.004	59	view →
LGG	OS	Median	All	0.368	0.549	<.001	54	view →
MESO	OS	Median	II,III,IV	0.277	0.768	.001	45	view →
KICH	OS	Median	All	1.000	0.698	.005	44	view →
SKCM	OS	Median	II,III,IV	0.386	0.233	.002	42	view →
KIRC	DFS	Tertile	All	0.846	0.704	.003	33	view →
UVM	OS	Median	III,IV	0.281	1.000	.003	31	view →
UCS	DFS	Tertile	IV	0.975	0.237	.024	30	view →
HNSC	DFS	Median	III,IV	0.388	0.224	.001	27	view →
DLBC	DFS	Median	All	0.606	1.000	.011	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

TCIM–STAD (DFS)

Open the STAD breakdown →