TCHP

Across TCGA patient cohorts, TCHP RNA expression is significantly associated with the protein abundance of many other proteins, with 16,621 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TCHP-associated proteins across cancer lineages are SART3, ZCCHC8, and SPEN_S727. Each is linked with TCHP in more than 6 cancer types. Because this analysis shows association rather than direction, both TCHP-to-partner and partner-to-TCHP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TCHP versus SART3 in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TCHP→partner) and Y-score (partner→TCHP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SART3 →	+0.286	+0.385	<.001	<.001	3	7
LUAD	ZCCHC8 →	+0.255	+0.493	<.001	<.001	3	5
PDAC	SPEN_S727 →	+0.485	+0.348	<.001	<.001	3	5
LSCC	TMPO →	+0.442	+0.628	<.001	<.001	3	5
GBM	SMNDC1 →	+0.368	+0.365	<.001	<.001	3	5
LSCC	PRPF4 →	+0.308	+0.607	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,621 associations by consensus.

TCHP vs SART3 — GBM

Explore this scatter interactively →