TCHHL1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, TCHHL1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TCHHL1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where TCHHL1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TCHHL1 is over-expressed in tumor.

LUSC and LUAD are the cancer types where TCHHL1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TCHHL1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUSCAllAll+0.173<.0017view →
LUADAllII,III,IV+0.037.0331view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

TCHHL1–LUSC

Tumor-vs-normal expression box plot for TCHHL1 RNA in LUSC.

Open the LUSC breakdown →

Exploration