TCHH

Across TCGA patient cohorts, TCHH RNA expression is significantly associated with the protein abundance of many other proteins, with 8,709 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TCHH-associated proteins across cancer lineages are ACTR2, OSTF1, and PITPNC1_S299. Each is linked with TCHH in more than 3 cancer types. Because this analysis shows association rather than direction, both TCHH-to-partner and partner-to-TCHH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TCHH versus ACTR2 in PDAC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TCHH→partner) and Y-score (partner→TCHH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ACTR2 →	+0.183	+0.175	<.001	.001	3	4
GBM	OSTF1 →	+0.475	+0.227	<.001	.002	3	3
GBM	PITPNC1_S299 →	-0.484	-0.263	<.001	.004	3	3
GBM	PLA2G15 →	+0.478	+0.331	<.001	<.001	3	3
GBM	RB1_T356 →	-1.041	-0.357	<.001	<.001	3	3
UCEC	S100A3 →	+0.940	+0.685	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,709 associations by consensus.

TCHH vs ACTR2 — PDAC

Explore this scatter interactively →