TCHH

Across TCGA cell cohorts, TCHH RNA expression is significantly associated with the go_rna of many other GO terms, with 1,936 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TCHH-associated GO terms across cancer lineages are Regulation of RNA splicing, Regulation of proteasomal protein catabolic process, and Regulation of mRNA processing. Each is linked with TCHH in more than 9 cancer types. Because this analysis shows association rather than direction, both TCHH-to-partner and partner-to-TCHH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by TCHH-low versus TCHH-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCHH→partner) and Y-score (partner→TCHH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of RNA splicing →	+0.098	+0.833	<.001	.002	3	10
STOMACH	Regulation of proteasomal protein catabolic process →	+0.047	+0.597	.006	.003	3	9
OESOPHAGUS	Regulation of mRNA processing →	+0.082	+0.390	<.001	<.001	3	8
OVARY	Protein-containing complex disassembly →	+0.055	+0.438	<.001	<.001	3	8
OESOPHAGUS	Regulation of transcription initiation by RNA polymerase II →	+0.075	+0.540	.001	<.001	2	9
PANCREAS	Telomere organization →	+0.042	+0.329	<.001	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,936 associations by consensus.

Regulation of RNA splicing by TCHH expression — STOMACH

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