Across TCGA cell cohorts, TCF4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,352 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TCF4-associated GO terms across cancer lineages are RNA localization, Epigenetic regulation of gene expression, and Nucleic acid transport. Each is linked with TCF4 in more than 13 cancer types. Because this analysis shows association rather than direction, both TCF4-to-partner and partner-to-TCF4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCF4→partner) and Y-score (partner→TCF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	RNA localization →	+0.100	+1.901	.001	.002	3	14
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.068	+2.250	<.001	<.001	3	13
OESOPHAGUS	Nucleic acid transport →	+0.113	+1.710	<.001	.001	3	13
OESOPHAGUS	RNA transport →	+0.113	+1.710	<.001	.001	3	13
OESOPHAGUS	Establishment of RNA localization →	+0.108	+1.953	.001	.001	3	13
OESOPHAGUS	RNA export from nucleus →	+0.127	+1.983	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,352 associations by consensus.

Exploration

TCF4 survival (RNA) · tumor vs normal (RNA) · all TCF4 data types