TCF3

Across TCGA patient cohorts, TCF3 RNA expression is significantly associated with the RNA expression of many other genes, with 19,698 significant associations in total. ACC shows the largest number of these associations.

The most reproducible TCF3-associated genes across cancer lineages are DOT1L, ILF3, and CSNK1G2. Each is linked with TCF3 in more than 32 cancer types. Because this analysis shows association rather than direction, both TCF3-to-partner and partner-to-TCF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TCF3 versus DOT1L in ACC, with a Pearson correlation of 0.81.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCF3→partner) and Y-score (partner→TCF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	DOT1L →	+1.373	+1.555	<.001	<.001	3	33
LIHC	ILF3 →	+1.067	+1.208	<.001	<.001	3	33
ACC	CSNK1G2 →	+1.154	+1.415	<.001	<.001	3	33
ACC	CPSF1 →	+0.922	+1.184	<.001	<.001	3	33
ACC	KHSRP →	+1.007	+1.513	<.001	<.001	3	33
ACC	REXO1 →	+0.841	+1.181	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,698 associations by consensus.

TCF3 vs DOT1L — ACC

Explore this scatter interactively →