TCF3

Across TCGA patient cohorts, TCF3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,151 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TCF3-associated genes across cancer lineages are TTK, PTBP1, and STMN1. Each is linked with TCF3 in more than 4 cancer types. Because this analysis shows association rather than direction, both TCF3-to-partner and partner-to-TCF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TCF3 versus TTK in LSCC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCF3→partner) and Y-score (partner→TCF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TTK →	+0.986	+0.468	<.001	<.001	3	5
LUAD	PTBP1 →	+0.387	+0.380	<.001	<.001	3	5
GBM	STMN1 →	+1.156	+0.775	<.001	<.001	3	5
HNSC	KIF18A →	+0.894	+0.384	<.001	.001	3	5
GBM	SMC2 →	+0.677	+0.708	<.001	<.001	3	5
HNSC	DNA2 →	+0.616	+0.306	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,151 associations by consensus.

TCF3 vs TTK — LSCC

Explore this scatter interactively →