TCF20

Across TCGA pan-cancer cohorts, TCF20 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TCF20 data layer compared with 22 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TCF20 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TCF20 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

COAD, CCRCC, and UCEC are the cancer types where TCF20 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.917	.019	18	view →
CCRCC	DFS	Tertile	II,III,IV	0.733	0.402	.015	8	view →
UCEC	DFS	Median	All	1.000	0.941	.038	4	view →
GBM	DFS	Median	All	0.776	0.660	.014	4	view →
PDAC	DFS	Median	III,IV	0.481	0.244	.014	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TCF20–COAD (DFS)

Open the COAD breakdown →