TCF20

Across TCGA patient cohorts, TCF20 protein abundance is significantly associated with the RNA expression of many other genes, with 14,513 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TCF20-associated genes across cancer lineages are ZNF74, PHF5A, and TMEM97. Each is linked with TCF20 in more than 6 cancer types. Because this analysis shows association rather than direction, both TCF20-to-partner and partner-to-TCF20 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TCF20 versus ZNF74 in HNSC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCF20→partner) and Y-score (partner→TCF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF74 →	+0.634	+0.283	.001	<.001	3	7
HNSC	PHF5A →	+0.734	+0.194	<.001	<.001	3	6
HNSC	TMEM97 →	+1.255	+0.294	<.001	<.001	3	6
HNSC	SNRPD3 →	+0.633	+0.217	<.001	<.001	3	6
HNSC	CCDC134 →	+0.610	+0.207	<.001	<.001	3	6
HNSC	POLDIP3 →	+0.788	+0.229	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,513 associations by consensus.

TCF20 vs ZNF74 — HNSC

Explore this scatter interactively →