TCF20

Across TCGA cell cohorts, TCF20 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,055 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TCF20-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Positive regulation of T-helper 17 cell lineage commitment, and Positive regulation of cell fate commitment. Each is linked with TCF20 in more than 17 cancer types. Because this analysis shows association rather than direction, both TCF20-to-partner and partner-to-TCF20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome condensation grouped by TCF20-low versus TCF20-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCF20→partner) and Y-score (partner→TCF20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of chromosome condensation →	+0.191	+0.651	.004	.009	3	18
OESOPHAGUS	Positive regulation of T-helper 17 cell lineage commitment →	+0.257	+0.815	.003	.003	3	17
BREAST	Positive regulation of cell fate commitment →	+0.198	+0.829	<.001	<.001	3	14
LUNG_SCLC	Regulation of protein localization to centrosome →	+0.176	+0.656	<.001	<.001	3	14
SOFT_TISSUE	Regulation of protein localization to nucleus →	+0.078	+0.788	<.001	<.001	3	14
STOMACH	Regulation of chromatin organization →	+0.093	+0.887	.006	.001	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,055 associations by consensus.

Negative regulation of chromosome condensation by TCF20 expression — OESOPHAGUS

Explore this box plot interactively →