TCF19

Across TCGA cell cohorts, TCF19 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,214 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TCF19-associated GO terms across cancer lineages are Regulation of mitotic sister chromatid separation, Regulation of chromosome separation, and Regulation of nuclear division. Each is linked with TCF19 in more than 17 cancer types. Because this analysis shows association rather than direction, both TCF19-to-partner and partner-to-TCF19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic sister chromatid separation grouped by TCF19-low versus TCF19-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TCF19→partner) and Y-score (partner→TCF19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of mitotic sister chromatid separation →	+0.135	+1.105	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome separation →	+0.125	+1.187	.002	.002	3	18
PANCREAS	Regulation of nuclear division →	+0.093	+0.983	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic sister chromatid separation →	+0.151	+1.378	.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of sister chromatid segregation →	+0.151	+1.378	.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic sister chromatid segregation →	+0.151	+1.378	.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,214 associations by consensus.

Regulation of mitotic sister chromatid separation by TCF19 expression — BREAST

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