TCERG1L

Across TCGA patient cohorts, TCERG1L mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCERG1L-associated genes across cancer lineages are EGFR_pY1068, eIF4E, and FoxM1. Each is linked with TCERG1L in more than 2 cancer types. Because this analysis shows association rather than direction, both TCERG1L-to-partner and partner-to-TCERG1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by TCERG1L-low versus TCERG1L-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCERG1L→partner) and Y-score (partner→TCERG1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	EGFR_pY1068 →	-0.616	-3.000	.013	.034	3	2
UCEC	eIF4E →	+0.164	+2.502	.010	.001	2	3
UCEC	FoxM1 →	+0.184	+1.754	.018	.001	3	2
UCEC	ACC1 →	+0.241	+1.887	.028	.029	3	2
COAD	JNK_pT183_Y185 →	-0.233	-3.450	.047	.005	3	2
UCEC	mTOR_pS2448 →	-0.110	-2.102	.014	.016	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

EGFR_pY1068 by TCERG1L expression — LUAD

Explore this box plot interactively →