TCERG1

Across TCGA patient cohorts, TCERG1 mutation is significantly associated with the total protein of many other genes, with 55 significant associations in total. COAD shows the largest number of these associations.

The most reproducible TCERG1-associated genes across cancer lineages are FoxM1, PCNA, and Cyclin-E2. Each is linked with TCERG1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TCERG1-to-partner and partner-to-TCERG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by TCERG1-low versus TCERG1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCERG1→partner) and Y-score (partner→TCERG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.176	+1.415	.028	.010	3	3
COAD	PCNA →	+0.323	+3.334	.002	.005	3	3
COAD	Cyclin-E2 →	+0.231	+3.593	.022	.001	3	3
UCEC	S6_pS240_S244 →	+0.307	+2.013	.014	.016	3	2
COAD	ATM →	-0.626	-3.321	<.001	.009	3	2
COAD	c-Met_pY1235 →	+0.089	+3.169	.042	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

FoxM1 by TCERG1 expression — UCEC

Explore this box plot interactively →