TCEANC2

Across TCGA patient cohorts, TCEANC2 mutation is significantly associated with the RNA expression of many other genes, with 888 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCEANC2-associated genes across cancer lineages are TRAJ35, MIR340, and MIR98. Each is linked with TCEANC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCEANC2-to-partner and partner-to-TCEANC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ35 grouped by TCEANC2-low versus TCEANC2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCEANC2→partner) and Y-score (partner→TCEANC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRAJ35 →	+0.755	+2.057	<.001	.003	3	2
BLCA	MIR340 →	+0.361	+5.497	<.001	.004	3	2
UCEC	MIR98 →	+0.231	+2.316	.001	.005	3	1
UCEC	CWC25 →	+0.397	+2.716	.005	.003	3	1
UCEC	CCL4L2 →	+0.986	+3.338	<.001	.005	3	1
UCEC	H2AC14 →	+0.847	+2.716	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 888 associations by consensus.

TRAJ35 by TCEANC2 expression — UCEC

Explore this box plot interactively →