TCEANC2

Across TCGA patient cohorts, TCEANC2 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCEANC2-associated genes across cancer lineages are 14-3-3_beta, Acetyl-a-Tubulin-Lys40, and MEK1. Each is linked with TCEANC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCEANC2-to-partner and partner-to-TCEANC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by TCEANC2-low versus TCEANC2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCEANC2→partner) and Y-score (partner→TCEANC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.121	-2.432	.003	.018	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.550	+2.469	.008	.010	3	1
UCEC	MEK1 →	+0.401	+2.321	.007	.006	3	1
UCEC	MSH2 →	-0.271	-2.295	.004	.033	3	1
UCEC	Myosin-IIa →	+0.232	+1.707	.003	.027	3	1
UCEC	P-Cadherin →	-0.124	-2.999	.036	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

14-3-3_beta by TCEANC2 expression — UCEC

Explore this box plot interactively →