TCEAL7

Across TCGA patient cohorts, TCEAL7 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCEAL7-associated genes across cancer lineages are 14-3-3_beta, EGFR_pY1068, and EGFR. Each is linked with TCEAL7 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCEAL7-to-partner and partner-to-TCEAL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by TCEAL7-low versus TCEAL7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCEAL7→partner) and Y-score (partner→TCEAL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.117	-3.143	.006	.018	3	1
UCEC	EGFR_pY1068 →	-0.291	-3.459	.006	.005	3	1
UCEC	EGFR →	-0.155	-3.000	.022	.036	3	1
UCEC	eIF4E →	+0.240	+3.013	.007	.018	3	1
UCEC	A-Raf_pS299 →	-0.189	-2.906	<.001	.001	3	1
UCEC	Fibronectin →	-0.302	-1.990	.030	.030	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

14-3-3_beta by TCEAL7 expression — UCEC

Explore this box plot interactively →