Across TCGA patient cohorts, TCEAL6 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCEAL6-associated genes across cancer lineages are Shc_pY317, TFRC, and Notch1. Each is linked with TCEAL6 in more than 2 cancer types. Because this analysis shows association rather than direction, both TCEAL6-to-partner and partner-to-TCEAL6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCEAL6→partner) and Y-score (partner→TCEAL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Shc_pY317 →	-0.239	-4.000	<.001	<.001	3	3
UCEC	TFRC →	+0.495	+1.678	.015	.023	3	3
UCEC	Notch1 →	+0.194	+2.009	<.001	.017	3	2
UCEC	EGFR_pY1068 →	-0.246	-3.321	.010	.009	3	1
UCEC	A-Raf_pS299 →	-0.154	-2.087	<.001	.005	3	1
UCEC	IGFBP2 →	-0.744	-1.678	.002	.023	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

TCEAL6 survival (RNA) · tumor vs normal (RNA) · all TCEAL6 data types