Across TCGA patient cohorts, TCEAL5 mutation is significantly associated with the total protein of many other genes, with 26 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TCEAL5-associated genes across cancer lineages are Caspase-7-cleavedD198, EGFR_pY1068, and eIF4G. Each is linked with TCEAL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TCEAL5-to-partner and partner-to-TCEAL5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TCEAL5→partner) and Y-score (partner→TCEAL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.837	+3.321	<.001	.009	3	2
UCEC	EGFR_pY1068 →	-0.256	-3.087	.011	<.001	3	1
UCEC	eIF4G →	+0.276	+1.906	.027	.016	3	1
UCEC	ERK2 →	+0.195	+1.906	.012	.016	3	1
UCEC	JNK_pT183_Y185 →	-0.195	-2.000	.003	.030	3	1
UCEC	Ku80 →	+0.236	+1.498	.012	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

TCEAL5 survival (RNA) · tumor vs normal (RNA) · all TCEAL5 data types