TCEAL4

Across TCGA pan-cancer cohorts, TCEAL4 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated TCEAL4 data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TCEAL4 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TCEAL4 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

HNSC, UCEC, and LUAD are the cancer types where TCEAL4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.773	0.971	.001	61	view →
UCEC	DFS	Median	III,IV	0.274	1.000	.002	28	view →
LUAD	OS	Median	II,III,IV	0.908	0.339	.003	7	view →
LSCC	OS	Quartile	All	0.795	0.950	.024	4	view →
CCRCC	OS	Median	IV	1.000	0.202	.034	4	view →
PDAC	DFS	Median	IV	0.766	0.234	.026	3	view →
GBM	DFS	Median	All	0.315	0.211	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TCEAL4–HNSC (OS)

Open the HNSC breakdown →